电子书版:
http://www.rheumas.cn/article.asp?id=52
Preface
Twenty-three years have passed since Bill Kelley, Clem Sledge, Shaun Ruddy, and I met with Jack Hanley at W.B. Saunders to plan production of The Textbook of Rheumatology. Our goal was to equal or better any current text that described clinical entities and their treatment, but to exceed by far the depth and breadth of existing text in the detail and explication of basic sciences that provide the infrastructure of rheumatology and orthopedic surgery. That first edition, thanks to the diligent writing of many contributors, exceeded our expectations. It became the best-seller of rheumatology texts.
The template for that first edition proved successful, and there has been no reason to change it for subsequent editions. When Bill Kelley stepped down as an active editor, we recognized the importance of "name recognition" and kept the title as Kelley's Textbook of Rheumatology while adding John Sergent and Ralph Budd as associate editors in the sixth edition published in 2001. Recognizing as well the reality that new and younger minds should be involved for the present as well as future editions, this seventh edition has seven editors. We added Gary Firestein and Mark Genovese to the group, and the result is highly amplified brain power. Supplementing Shaun, and Ted, and Clem is the basic science knowledge of Gary and Ralph and the clinical science backgrounds of John and Mark. The future of Kelley's Textbook of Rheumatology is secure.
This seventh edition was planned with full awareness that we are in the midst of remarkable change in the sciences that form the base of rheumatology. Over the past 70 years we have seen the birth and growth of immunology, biochemistry, cell biology, and genetics. Each of these specialities grew with remarkable independence from the others until recent years. The future of our specialty is now intimately associated with integrative science. Recombinant technology now links genetics with biochemistry, and more important, the translational science that has evolved often enables us to leapfrog directly over traditional basic science to understanding of clinical disease states. Just as in neurobiology, where studies of the basis of consciousness involve psychology, philosophy, mathematics, and computer science, the unraveling of complex diseases such as systemic lupus erythematosus will require collaborative ventures by immunologists, immunogeneticists, biochemists, and cell biologists. Ironically, each of these specialists is using the same molecular tools, and so added to the team must be those who are developing the next methods that will supplant the micro-arrays, Western and Southern blots, and knock-out mice.
It is with the likelihood that this integrative collaboration that can bring true synergism to the understanding of rheumatic disease that this edition of Kelley's Textbook of Rheumatology has been planned. Each of the chapters in the section on the basic sciences describes well both the present and future opportunities for application of these specialized data to specific diseases, and each chapter on pathogenesis of specific diseases refers frequently to the advances that science brings to clinical science.
In this seventh edition an accompanying DVD, organized and edited by Shaun Ruddy, provides expansion of clinical photographs, histopathology, and detailed videos of the musculoskeletal system and arthroscopic views of diseased joints.
The corollary of this burst of basic science that can be clearly integrated with clinical science is the need for frequent updates for our readers, updates that fill the gaps between subsequent editions. In response, we are providing "e-ditions" in the format of a web site that will provide every reader with the latest data and their interpretations that will enable basic scientists to plan new experiments, and clinicians to better diagnose and treat their patients.
While we recognize that the future of paper texts is indeterminate amidst the electronic revolution, we are satisfied that this seventh edition of Kelley's Textbook of Rheumatology will serve readers better than any other source of information about rheumatology, orthopedic approaches to rheumatic diseases, and the science that drives understanding of the pathogenesis and treatment of the afflictions that our patients suffer from.
Copyright © 2007 Elsevier Inc. All rights reserved.

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